Beyond that, the count of mf per mg of skin or per skin snip of standardized weight is also a measure of infection intensity. volvulus infection compared to nodule palpation. The detection of mf in skin biopsies (skin snips) allows a more sensitive and specific diagnosis of O. Adult parasites can produce an estimate of 1300–1900 larvae (microfilaria, mf) per day which invade the dermis of the host to be newly incorporated with the blood meal of the vector fly. Subcutaneous nodules can be used for diagnosis of onchocerciasis although this is of limited sensitivity because deeply seated nodules cannot be located by palpation. Sex: Throughout all ages, males are more frequently infected than females in most endemic areas.įollowing infection of the human host the parasite develops into adult worms of considerable size (length up to 50 cm for female worms) and aggregates within nodules which can be located in the sub-cutaneous layer of the skin but also in internal parts of the body.Especially in non-stable populations the time point of immigration has to be taken into account. volvulus endemic area, this coincides with the age of the inhabitants. Time (duration) of exposure: For those born in an O. ![]() Place of residence, usually specified as village of residence, is therefore considered a valid indicator of intensity of exposure.
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